James Campbell Hopkins (April 27, 1819 – September 3, 1877) was a United States federal judge.
Born in Pawlet, Vermont, Hopkins read law to enter the bar in 1845. He was in private practice in Granville, New York from 1845 to 1853, and was the postmaster of Granville from 1850 to 1855. He was a member of the New York State Senate from 1853 to 1855, returning to private practice in Madison, Wisconsin from 1856 to 1870.
On July 9, 1870, Hopkins was nominated by President Ulysses Grant to a new seat on the United States District Court for the Western District of Wisconsin created by 16 Stat. 171. He was confirmed by the United States Senate on July 9, 1870, and received his commission the same day. While on the bench, he was a professor at the University of Wisconsin Law School in Madison from 1876 to 1877. Hopkins served on the bench until his death, in 1877, in Madison.